Want to smooth out those crows feet around your eyes or perhaps get rid of those wrinkles along your forehead? BotoxÂ® and DysportÂ® are both injectable cosmetic wrinkle smoothing agents and yes, they both really work. Basically they temporarily relax or paralyze the muscles in the face that create expressions, such as frown lines between the brows, that over time result in visible facial lines and deeper creases. Undesirable lines become smoothed out giving you a more relaxed and youthful appearance.
Botox injectiosn are most often used on forehead lines, crow’s feet (lines around the eye) and frown lines. Wrinkles caused through sun exposure and gravity cannot be treated.
BotoxÂ® has been used effectively for cosmetic purposes in the United States for a series of years now whereas DysportÂ® has just been approved for use (although is has been used safely for many years throughout Europe, Brazil and more than 26 other countries worldwide) and is currently (as of July 2009) available at your doctors office along side BotoxÂ®.
The Details: Botox
Although they’re similar in function, they’re longer the same drug, they have different dosages and different possible side effects. It’s up to you to be informed when selecting between the two and hopefully after reading this page you’ll be.
Botox has an interesting history that all began with sausage in the 1820’s. A German doctor, Dr. Justinus Kerner began some experiments to determine what resulted in the deaths of some Germans who had consumed sausage. Turns out it was food-borne botulism. Then in 1895 Dr. Emile Van Ermengem from Belgium was the first person to isolate the bacteria, and in 1944 Dr. Edward Schantz cultured Clostridium botulinum and isolated the toxin. And finally in 1949, it was discovered that botulinum toxin blocks neuromuscular transmission. In the 1950’s and 60’s purified botulinum toxin type A into crystalline form was synthesized and it was found that small doses of botulinum relax muscles temporarily. In the 1950s the toxin started to be used experimentally as a medical cosmetic treatment on politicians, one of which was said to become the actor and former United States President, Ronald Regan. The 70’s and 80’s brought many experiments, mostly on animals with the toxin.
This Could Lead To Other Ideas
Finally, in 1989-a year after the company Allergen bought the distribution rights to the toxin-the FDA approved botulinum toxin type A for treating crossed eyes and spasms in the eye muscle. Soon after than Botox was born. As more research was carried out in the 1990 ‘s, it was uncovered that Botox temporarily cured excessive sweating and cerebral palsy. Then ophthalmologist Dr. Jean Carruthers noticed her patients treated with Botox were looking fabulously wrinkle-free. She and he husband, (a dermatologist) published a study on Botox’s ability to decrease frown lines and after that Botox took off as a cosmetic treatment. So much so that during the late 90’s they even ran out of it temporarily.
Botox is used in a dilute solution in treating wrinkles. This type of Botox solution is usually known as Botox type A and so far is the more popular and widely used one in this treatment.
Side effects are possible, as with any drug. Most people however, don’t experience any and tolerate the drug quite well. If side effects do occur they’re usually very mild.
Botox has been studied thoroughly in clinical trials. In these studies, common side effects included: droopy eyelids, nausea, muscle weakness, facial pain, dyspepsia, tooth problems, high blood pressuire, flu-like symptoms, such as a fever and chills, lightheadedness, weakness, hemorrhage, or infection at the injection site.
Some side effects with Botox, while occurring infrequently, are potentially serious and needs to be reported to your healthcare provider right away. These include but aren’t limited to: chest pain, difficulty swallowing, dry eyes, eye pain, or speech problems, double vision, signs of an allergic reaction such as rash, urticaria, itching, wheezing, swelling.
Recently there has been news of Botox possibly being able to spread beyond the site of injection, potentially causing botulism poisoning. Accusations against Botox earlier this year led the FDA to mandate black box warnings for the popular drug, however it is inconclusive with respect to whether or not this can actually happen as of yet.
Dysport is a lyophilized form of the botulinum toxin type, like Botox. The difference is that a vial of Dysport contains 500 Units of toxin and 125 micrograms of albumin, and is typically diluted to 200 U/mL. The Botox vial contains 100 Units of toxin and 500 micrograms of albumin, and is typically diluted to 25-50 U/mL. Dysport works along the same way Botox does by preventing muscle contraction and weakening the muscles.
The early 90’s when Dyspoirt first came into use as a treatment for muscle spasms in the UK. Like Botox, it was then discovered that Dysport could effectively remove wrinkles and facial creases as well, the treatment was distributed in Europe and several other countries all over the world.
Botox treatment can reduce the appearance of frown lines, forehead wrinkles and crows feet around the eyes. It can also be used in order to treat creases around the mouth. When performed properly it is expected to have a gentle relaxing effect while still allowing natural expressions like smiling and frowning. Botox treatment won’t reduce lines caused by sun damage and can only be fully effective on very deep creases.
In 2006, Dysport’s manufacturer, Ipsen, joined forces with the U.S. pharmaceutical group, Medicis, to distribute the product in the U.S. and Canada. The U.S. branding of Dysport was originally going to be Reloxin, but the FDA mandated that the drug be branded under its original name of Dysport. Most news and online sources, originally discussed it under the name Reloxin.
Currently Dysport is the only other injectable type in Botox’s class giving Botox some stiff and much needed competition. I say this because Botox is very expensive. Currently, the cost of Botox injections can range from $300 to $500 per treatment. The cost of Dysport, on the other hand, starts out more firmly near the $300 mark. (you can hope to save around 10% with disport basically) It would therefore make sense that over time if Botox feels threatened by Dysports success, the makers of Botox, Allergan, could wind up reducing the cost of Botox to remain competitive.
Side effects are possible, as with any drug. Most people, just like with Botox, don’t experience any and tolerate the drug quite well. If side effects do occur they’re usually very mild and the more common include: nose and throat irritation, headache, injection site pain, injection site skin reaction, upper respiratory tract infection, eyelid swelling, eyelid drooping, nausea, and sinus inflammation. These are all the same side effects associated with Botox.
I really couldn’t find any additional side effects or different side effects related to Dysport when I researched for this article.
Like Botox, the labeling for Dysport also contains a boxed warning about the potential distant spread of all botulinum toxin products to other parts of the body.
Botox and Dysport have been administered to over 21 million people during the past decade with very few complications. However, to be sure your results are of the quality you want and are also complication free, you need to be choosy in where you go to get the injections done. There are many out there, including physicians, who’re not trained in medical aesthetics, and who lack lack the training and certification necessary to ensure the security and splendid results.
Be wary of places the sell Botox or Dyspot by the area such as: forehead = $600, crows feet = $400 and so on. These places are usually ripping you off! You never know just how much of the good you’re actually having injected and whether or not it is an efficient and proper dose. Botox and Dysport come in UNITS. The unit relates to a measure of activity. Units are how doctors think about and use Botox.
A vial of Botox or Dysport comes with no fluid in it, just dried powder. The doctor’s office fills the vial with a degree of volume of saline to reconstitute the Botox or Dysport and draws up the amount to be injected into a syringe. Offices use between one and four milliliters of saline for this purpose. So, a one-milliliter syringe might contain between 25 to 100 units of Botox or Dysport. However, some offices dilute their Botox or Dysport much more. I even heard of one doctor who boasts of diluting a vial of Botox with 20 milliliters of saline, so each one-milliliter syringe contains only 5 units of Botox. This saves them money but costs you more so be wary.
There is a huge treatment difference in the results you’ll notice between 100 units of Botox or Dysport and 5 units of Botox or Dysport. So pin the office down. Make them tell you how many units they use and if they’re an ethical office, they’ll have no hesitation telling you.
Excessive sweating: Underarm sweating can be eliminated with Botox. The palms, face, and feet can also possibly be treated.
Migraine headaches: Migraine sufferers can get relief by getting Botox injections into the back or shores of the head, forehead or brow area.
Cerebral Palsy and Multiple Sclerosis :Recently, Botox has been used to treat people with Multiple Sclerosis as it lessens muscle contractions that cause spasms and stiffness. Botox has also served as for years to treat children with Cerebral Palsy-it relaxes the muscles that are in spasm..
Muscle spasms and eye twitching: Involuntary eyelid closure, face, jaw and neck spasms, vocal chord spasms, eye twitching, and even stuttering can be lessened with Botox injections.
Lift saggy breasts: Doctors in Europe and Canada are now injecting the pectoral muscles with Botox, to temporarily lift the breast tissue. Unfortunately, this only works on women with smaller breasts.
Sculpt the face: Skilled injectors, can use Botox to sculpt the face, turning up the nose, lifting the eyebrows, and puffing the lip out It can likewise be used at the parts of the mouth to slightly turn them up, and to ease the muscles in the chin, reducing the appearance of ‘golf ball chin’.
Relax bands in neck: As Some people develop vertical bands in the neck. This can be softened with Botox. The effect can also simulate a neck lift.
Prostate: Men who’ve had their prostate injected with Botox have seen a decline in its size. Relief from a number of the side effects associated with an enlarged prostate.
Overactive bladder: Doctors can inject Botox into the basis of the bladder to alleviate the problems associated with an overactive bladder.
Currently Botox isn’t FDA-approved for a number of these treatments and part of the uses for Botox have only been carried out on a handful of patients.